Relationship Between Hyperventilation Syndrome and SARS-CoV-2 Infection

Completed

• Conditions: COVID-19; Hyperventilation Syndrome
• Interventions: Other: Nijmegen questionnaire score

• Registration Number: NCT05224830
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

Following an acute COVID-19 infection, many patients suffer from long lasting physical symptoms that may greatly impair quality of life. Persisting dyspnea and other functional respiratory complaints could evoke Hyperventilation Syndrome (HVS) as a putative contributor of the long-COVID presentation in COVID-19 survivors. We aimed to assess the possible relationship between a HVS and previous acute SARS-CoV-2 infection.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-01
• Status Verified: 2022-02
• Study First Submitted: 2022-02-03
• Study First Submitted QC: 2022-02-03
• Study First Posted: 2022-02-04
• Primary Completion: 2022-05-01
• Study Completion: 2022-07-01
• Last Update Submitted: 2022-09-06
• Last Update Posted: 2022-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2846

Inclusion Criteria

• Read and speak French
• Perform a pulmonary function test

Exclusion Criteria

• incomplete questionnaire or inability to obtain an interpretable lung function assessment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
No presence of Hyperventilation Syndrome (HVS-).	Nijmegen questionnaire score	Study population was divided into two groups according to the diagnosis of Hyperventilation Syndrome HVS - : Nijmegen questionnaire score \< 24/64
Presence of Hyperventilation Syndrome (HVS+)	Nijmegen questionnaire score	Study population was divided into two groups according to the diagnosis of Hyperventilation Syndrome HVS +- : Nijmegen questionnaire score \> 23/64

Primary Outcome Measures

Name	Time	Method
Assess the relationship between a hyperventilation syndrome and previous acute SARS-CoV-2 infection.	Nijmegen questionnaire during 15 minutes (cross-sectional monocentric study)

Secondary Outcome Measures

Name	Time	Method
Assess the relationship between a hyperventilation syndrome and dyspnea	Nijmegen questionnaire during 15 minutes (cross-sectional monocentric study)

Trial Locations

Locations (1)

Centre Hospitalier Régional Universitaire de Nancy.; 🇫🇷 Vandoeuvre les nancy, France