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IMT Outcomes in Sufferers of Severe Walking Disabilities and Intensive Care Unit Acquired Weakness

Not Applicable
Recruiting
Conditions
Intensive Care Unit Acquired Weakness
Interventions
Behavioral: Threshold IMT and traditional physical therapy program
Behavioral: traditional physiotherapy program
Registration Number
NCT06210763
Lead Sponsor
Cairo University
Brief Summary

Intensive care unit-acquired weakness (ICU-acquired weakness) may be caused by a variety of different causes. Several studies have shown that ICU-acquired weakness occurs in up to 30% of critically ill patients. It affects daily activities, walking, and functional performance

Detailed Description

Forty ICU-acquired weakness elderly patients will be randomly assigned to group A and group B, 20 elderly for each. Both groups will receive chest physiotherapy (cough training, vibration, percussion, rib springing, and postural drainage), 30 minutes of resisted training on upper- and lower-limb muscles (15 min on upper limb and 15 min on lower limb), and 30 minutes of neuromuscular electrical stimulation of lower- and upper-limb muscles (triceps and wrist extensors, dorsiflexors, and quadriceps). sessions will be executed 5 times weekly). Group A only will receive 3-set IMT (two sessions daily via threshold IMT, the set contain 10 repetitions) 5 times weekly. The study duration will be 1 month.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
40
Inclusion Criteria
  • sufferers with intensive care unit acquired weakness
  • Older sufferers patients with severe walking disability detected by Modified Functional Ambulation Category test,
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Exclusion Criteria
  • lower limb amputations
  • orthopedic or spinal disc disorders
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
group AThreshold IMT and traditional physical therapy programtwenty ICU-acquired weakness elderly patients will receive chest physiotherapy (cough training, vibration, percussion, rib springing, and postural drainage), 30 minutes of resisted training on upper- and lower-limb muscles (15 min on upper limb and 15 min on lower limb), and 30 minutes of neuromuscular electrical stimulation of lower- and upper-limb muscles (triceps and wrist extensors, dorsiflexors, and quadriceps). sessions will be executed 5 times weekly). this Group will receive 3-set IMT (two sessions daily via threshold IMT, the set contain 10 repetitions) 5 times weekly. The study duration will be 1 month.
group Btraditional physiotherapy programtwenty ICU-acquired weakness elderly patients will receive chest physiotherapy (cough training, vibration, percussion, rib springing, and postural drainage), 30 minutes of resisted training on upper- and lower-limb muscles (15 min on upper limb and 15 min on lower limb), and 30 minutes of neuromuscular electrical stimulation of lower- and upper-limb muscles (triceps and wrist extensors, dorsiflexors, and quadriceps). sessions will be executed 5 times weekly). The study duration will be 1 month.
Primary Outcome Measures
NameTimeMethod
Modified Functional Ambulation Category Testit will be measured after 1 month

it is a category test used to assess walking disability

Secondary Outcome Measures
NameTimeMethod
inspiratory muscle strengthIt will be measured after 1 month

it will be measure in cm H2O

six-minute walk test,It will be measured after 1 month

distance walked in 6 minute

physical division of short form 36It will be measured after 1 month

it assess physical component of short form 36 quality of life questionnare

Partial Pressure of carbon dioxideIt will be measured after 1 month

it is an arterial blood gas test

Oxygen saturationIt will be measured after 1 month

it is an arterial blood gas test

expiratory muscle strengthIt will be measured after 1 month

it will be measure in cm H2O

time up and go testIt will be measured after 1 month

it is time used to walk a three-meter distance

functional vital capacityIt will be measured after 1 month

the percentage of predicted value of functional vital capacity will be assessed

10-meter walking testIt will be measured after 1 month

it is time used to walk a 10-meter distance

mental division of short form 36It will be measured after 1 month

it assess mental component of short form 36 quality of life questionnare

forced expiatory volume in the first second of expirationIt will be measured after 1 month

the percentage of predicted value of FEV1 will be assessed

Partial Pressure of OxygenIt will be measured after 1 month

it is an arterial blood gas test

30-second sit to standIt will be measured after 1 month

number of (sit to stand) done in 30 seconds

Trial Locations

Locations (1)

Cairo Unoversity

🇪🇬

Giza, Egypt

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