Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
- Conditions
- InfantFood, FortifiedDietary Supplements
- Registration Number
- NCT01216709
- Lead Sponsor
- Umeå University
- Brief Summary
Iron deficiency (ID) affects up to 25% of Swedish infants and severe ID is associated with cognitive and behavioral problems. To avoid this, iron supplements or iron-fortified infant foods are recommended for infants. However, the optimal iron dose and mode of delivery have not yet been established. This is a concern as excessive iron intake may impair growth and increase morbidity in iron-sufficient infants. Previous studies have suggested that iron-fortified foods may have different effects than iron supplements. In this study, the investigators will investigate whether the mode of iron administration (supplementation vs. fortification) and the amount consumed (high intakes vs. low intakes) affect iron absorption, iron utilization, and zinc absorption in healthy term non-iron-deficient 6-month-old infants.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 72
- 6-7 months of age at the start of intervention
- healthy at enrollment
- full-term (>37 gestational weeks at birth)
- birth weight >2500 g
- predominantly bottle-fed at recruitment
- iron deficiency at enrollment
- previous or current use of iron supplements
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method iron absorption 1 month after enrollment
- Secondary Outcome Measures
Name Time Method indicators of iron metabolism, growth, and oxidative stress 1 month and 1.5 months after enrollment zinc absorption 1 month after enrollment
Trial Locations
- Locations (1)
Department of Clinical Sciences, Pediatrics, Umeå University Hospital
🇸🇪Umeå, Sweden
Department of Clinical Sciences, Pediatrics, Umeå University Hospital🇸🇪Umeå, Sweden