Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized Trial
Not Applicable
Completed
- Conditions
- Gastroesophageal Reflux DiseaseLaparoscopic Antireflux Surgery
- Registration Number
- NCT01321294
- Lead Sponsor
- General Public Hospital Zell am See
- Brief Summary
The aim of this study is to compare subjective and objective outcome and surgical "side effects" of Nissen and Toupet fundoplication performed in a single institution by only two surgeons and to compare pre and postoperative findings to healthy individuals.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Clinical diagnosis of gastroesophageal reflux disease
- Long history of GERD symptoms
- Persistent or recurrent symptoms despite optimal medical treatment
- Persistent or recurrent complications of GERD
- Reduced quality of life owing to increasing esophageal exposure to gastric juice
- Pathological values in the preoperative evaluated functional parameters
Exclusion Criteria
- Previous esophageal or gastric surgery
- Poor physical status (American Society of Anesthesiologists (ASA) scores III and IV)
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the differing outcomes of Nissen and Toupet fundoplication in GERD patients?
How does laparoscopic Nissen fundoplication compare to Toupet in terms of long-term symptom resolution and esophageal function metrics?
Which biomarkers correlate with successful postoperative outcomes in laparoscopic antireflux surgery for GERD with hiatal hernia?
What are the incidence rates of postoperative dysphagia and gas bloat syndrome between Nissen and Toupet fundoplication techniques?
How do laparoscopic Nissen and Toupet fundoplication outcomes compare to magnetic sphincter augmentation in GERD treatment?
Trial Locations
- Locations (1)
General Public Hospital Zell am See
🇦🇹Zell am See, Salzburg, Austria
General Public Hospital Zell am See🇦🇹Zell am See, Salzburg, Austria