Type of anesthesia in surgical conditions and postoperative recovery in laparoscopic surgery : a randomized trial comparing propofol-remifentanil total i.v. anesthesia with sevoflurane-remifentanil anesthesia.
- Conditions
- Neoplasms
- Registration Number
- KCT0006917
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 130
Adult patients scheduled for elective laparoscopic colorectal cancer surgery (anterior resection, lower anterior resection, hemicolectomy) in which the main surgical procedure was expected to last for more than 1 hour were screened for eligibility.
- Patients simultaneously participating in other studies
- Patients scheduled to be transfered to the intensive care unit after surgery
- Patients with a severe grade obstructive or restrictive pattern on PFT
- High risk (expected postoperative event > 5%) in cardiologic consultation
- Patients with reduced renal function expected to delay recovery when using rocuronium due to severe renal impairment (Cr > 1.5mg/dL, eGFR < 40 mL/min/1.73m2)
- Patients with Obesity BMI>40kg/m2
- Patients with known allergies to medications or foods
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of fatigue on the 1st day after surgery (with Chalder Fatigue Scale questionnaire )
- Secondary Outcome Measures
Name Time Method Body composition analysis using Inbody(Phase angle, Body Cell Mass, Skeletal mass index, ECW ratio);QoR-15 questionnaire;Incidence of fatigue (with Chalder Fatigue Scale questionnaire );Pain score and cumulative analgesics;adverse events (Nausea, vomiting, lowest saturation, urinary retention, pneumonia, atelectasis, reoperation);The surgeon's evaluation the conditions of the surgical field;the number of requirements of intraperitoneal injection pressure and peak pressure;Data about anesthesia during surgery