Multicenter Prospective Registry Study of Diffuse Large B Cell Lymphoma

• Conditions: Diffuse Large B Cell Lymphoma; Neutropenia, Febrile

• Registration Number: NCT02474550
• Lead Sponsor: Ajou University School of Medicine

Brief Summary

This study was designed to review clincal outcomes of Diffuse Large B Cell Lymphoma (DLBCL) treated with R-CHOP chemotherapy in the era of pegylated-filgrastim. The investigators will prospectively collect clinical data and treatment outcome of patients with DLBCL who use prophylactic pegylated-filgrastim.

Detailed Description

* Newly diagnosed DLBCL patients treated with R-CHOP chemotherapy

* Prphylactic peg-filgrastim on the day after chemotherapy

Study Timeline

• Study Start: 2015-04
• Study First Submitted: 2015-06-15
• Study First Submitted QC: 2015-06-15
• Study First Posted: 2015-06-17
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-25
• Last Update Posted: 2017-01-26
• Primary Completion: 2018-12
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• 19 or older
• newly diagnosed with DLBCL
• R-CHOP chemotherapy
• offer informed consent

Exclusion Criteria

• other subtype of NHL
• concomitant other cancer
• previous chemotherapy or radiotherapy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence of febrile neutropenia	within 30 days

Secondary Outcome Measures

Name	Time	Method
incidence of chemotherapy-related adverse events other than febrile neutropenia	4 weeks after completion of chemotherapy
Overall survival	2 year

Trial Locations

Locations (24)

Ajou Universtiy School of Medicine; 🇰🇷 Suwon, Kyeonggi, Korea, Republic of

Soon Chun Yang University Hospital Bucheon; 🇰🇷 Bucheon, Korea, Republic of

Busan Paik Hospital; 🇰🇷 Busan, Korea, Republic of

Chungbuk National University Hospital; 🇰🇷 Cheongju, Korea, Republic of

Keimyung Univerisity Dongsan Medical Center; 🇰🇷 Daegu, Korea, Republic of

Yeungnam University Hospital; 🇰🇷 Daegu, Korea, Republic of

Chungnam National University Hospital; 🇰🇷 Daejeon, Korea, Republic of

Inje University Ilsan Paik Hospital; 🇰🇷 Ilsan, Korea, Republic of

Gachon University Gill Hospital; 🇰🇷 Incheon, Korea, Republic of

Chonbuk Nationa University Hospital; 🇰🇷 Jeonju, Korea, Republic of

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