NCT01034865已完成不适用
Risk Factors and Molecular Genomics for Hepatocellular Carcinoma in U.S. Patients With Chronic Liver Disease: A Case Control Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 750
- 试验地点
- 1
研究概览
简要总结
To identify risk factors for the development and diagnosis of hepatocellular CA in patients with chronic hepatitis C and to use the data to ultimately develop an effective screening program.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For both experimental subjects and controls:
- •Patients between older than 18 years of age of all ethnic backgrounds and genders.
- •Patients with chronic liver disease
- •For Experimental Subjects Only:
- •Patients with HCC with a hepatic mass larger or equal to 5cm
- •Patients with HCC with a hepatic mass lesion confirmed by fine needle aspirate (FNA) or by pathology in the cases of surgical resection
- •Patients with HCC with a hepatic mass lesion with characteristic CT or MRI or angiographic appearance.
- •For Controls Only:
- •Patients with chronic liver disease without evidence of HCC confirmed by either :
- •A normal AFP level
- •a negative imaging study (ultrasound, CT, or MR imaging).
- •Negative liver cancer on explants.
排除标准
- •Patients who declined to participate in the study
- •Patients with a history of HIV infection
- •Patients with concurrent advanced malignancy of non-hepatic origin.
- •Patients with significant use of androgenic steroid.
- •Patients with exposure to vinyl chloride.
研究者
Mindie H. Nguyen
Associate Professor of Medicine
Stanford University
研究点 (1)
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