Risk Factors and Molecular Genomics for Hepatocellular Carcinoma in U.S. Patients With Chronic Liver Disease: A Case Control Study

Stanford University1 site in 1 country750 target enrollmentMay 2001

ConditionsCarcinoma, Hepatocellular

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Carcinoma, Hepatocellular
Sponsor: Stanford University
Enrollment: 750
Locations: 1
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

To identify risk factors for the development and diagnosis of hepatocellular CA in patients with chronic hepatitis C and to use the data to ultimately develop an effective screening program.

Registry

clinicaltrials.gov

Start Date

May 2001

End Date

June 2009

Last Updated

9 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Stanford University

Responsible Party

Principal Investigator

Mindie H. Nguyen

Associate Professor of Medicine

Stanford University

Eligibility Criteria

Inclusion Criteria

•For both experimental subjects and controls:
•Patients between older than 18 years of age of all ethnic backgrounds and genders.
•Patients with chronic liver disease
•For Experimental Subjects Only:
•Patients with HCC with a hepatic mass larger or equal to 5cm
•Patients with HCC with a hepatic mass lesion confirmed by fine needle aspirate (FNA) or by pathology in the cases of surgical resection
•Patients with HCC with a hepatic mass lesion with characteristic CT or MRI or angiographic appearance.
•For Controls Only:
•Patients with chronic liver disease without evidence of HCC confirmed by either :
•A normal AFP level