The Effect of Intravenous Tranexamic Acid and Interscalene Block Applied on Shoulder Arthroscopy

Not Applicable

• Conditions: Nerve Block; Tranexamic Acid
• Interventions: Other: interscalene block; Drug: tranexamic acid; Other: general anesthesia

• Registration Number: NCT04419246
• Lead Sponsor: Bursa Yüksek İhtisas Education and Research Hospital

Brief Summary

Nerve blocks are used for pain and surgery after many operations today. It has been demonstrated by studies that the amount of postoperative bleeding decreases. On the other hand, surgical teams can use additional medications, such as Tranexamic acid, which have been proven by different studies that have reduced bleeding during and after arthroscopic surgery.

Detailed Description

The investigators aimed to investigate the effect of interscalene block application and tranexamic acid on bleeding in shoulder arthroscopy operation.

Study Timeline

• Status Verified: 2020-06
• Study First Submitted: 2020-06-03
• Study First Submitted QC: 2020-06-04
• Study First Posted: 2020-06-05
• Last Update Submitted: 2020-06-06
• Last Update Posted: 2020-06-09
• Study Start: 2020-07-15
• Primary Completion: 2020-07-15
• Study Completion: 2021-07-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients who were in the American Society of Anesthesiologists (ASA) I-III class
• underwent elective shoulder arthroscopy
• Patients with consent to participate in the study

Exclusion Criteria

• history of arterial or venous thromboembolic disease
• Bleeding diathesis disorder
• Allergy to local anesthetics
• cardiac stent placement

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group I	interscalene block	interscalene block + General anesthesia
Group I	general anesthesia	interscalene block + General anesthesia
Group T	tranexamic acid	Tranexamic acid +General anesthesia
Group T	general anesthesia	Tranexamic acid +General anesthesia
Group S	general anesthesia	General anesthesia

Primary Outcome Measures

Name	Time	Method
serum hemoglobin exchange	preoperative, postoperative 1st and 2nd day	change of serum hemoglobin before and after operation

Secondary Outcome Measures

Name	Time	Method
postoperative bleeding amount	postoperative 24 hours	The volume of drainage
Visual Analog Scale	Postoperative 24 hours	Visual Analog Scale was used for pain.Pain intensity was measured using 0-10 cm visual analogue scale (VAS). (0= no pain, 10=intolerable pain)