To check the efficacy of calcium hydroxide, triple antibiotic paste and metapex in treatment of infected immature teeth

Phase 2

Completed

Conditions: fractured non vital maxillary anterior teeth

Registration Number: CTRI/2018/05/014310

Brief Summary: In this study, materials used other than calcium hydroxide are Metapex and Triple antibiotic paste. Metapex is a combination of calcium hydroxide and iodoform in which advantages of Ca(OH)2 and antiseptic activity of Iodoform is clubbed. Whereas,Triple antibiotic paste (mixture of metronidazole, doxycycline and minocycline in same amount) allows complete disinfection of canals thus helps in keeping sterile canals and promote apexification.

Purpose of this study is to compare efficacy as well as time taken for formation of apical barrier using combination of calcium hydroxide and iodoform (metapex) in apexification of traumatized or carious necrotic immature permanent teeth. Newer techniques have recently evolved as treatment options for immature necrotic teeth revascularization and tissue engineering. More research is required in this field.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 30

Inclusion Criteria

CHILDREN WITH TRAUMATIZED NON VITAL PERMANENT MAXILLARY INCISORS,DELAYED RESPONSE TO PULP VITALITY TESTS, ADEQUATE BONE SUPPORT, NO MOBILITY, GOOD RESTORABILITY.

Exclusion Criteria

TEETH HAVING PATHOLOGIC RESORPTION,HORIZONTAL OR VERTICAL ROOT FRACTURES, PERIAPICAL INFECTION MORE THAN 3 mm IN SIZE, CHILDREN WITH COMMUNICABLE OR SYSTEMIC DISEASES, MENTAL RETARDATION, HISTORY OF PREVIOUS TREATMENT, ANKYLOSIS.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
UNEVENTFUL GROWTH OF ROOT APEX AND CLOSURE OF APEX	1,3 and 6 months postoperatively

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Nair hospital dental college
🇮🇳
Mumbai, MAHARASHTRA, India
Nair hospital dental college
🇮🇳Mumbai, MAHARASHTRA, India
SAYALI MALI
Principal investigator
9665943624
sayali.mali1227@gmail.com