Evaluation of Multimodal Monitoring Technologies in the Peri-operative Care of Cardiac Surgical Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Right ventricular failure
研究概览
简要总结
The purpose of this prospective observational cohort study is to evaluate multimodal monitoring technologies in the perioperative care of cardiac surgical patients. Right ventricular pressure tracings, near infrared spectroscopy (NIRS) and transthoracic ultrasonography will be studied for their ability to detect and predict complications such as right ventricular failure, renal failure and respiratory failure.
详细描述
The study has 4 main objectives:
- To determine if right ventricular pressure tracings correlate with other indices of right ventricular failure and with positive fluid balance, renal failure and increased length of stay in the intensive care unit.
- To determine the prevalence of portal vein pulsatility in the perioperative period and its association with right ventricular failure and positive fluid balance.
- To determine if Near InfraRed Spectroscopy (NIRS) values correlate with mixed venous oxygen saturation (SvO2) and with poorer post-operative prognosis.
- To determine the incidence, risk factors and prognosis of respiratory complications of cardiac surgery using transthoracic ultrasonography.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cardiac surgery performed at the Montreal Heart Institute
- •18 years old and older
排除标准
- •Urgent surgery
- •Pre-operative intra-aortic balloon pump, left ventricular assist device or ECMO
- •Heart transplant
- •Cirrhosis
结局指标
主要结局
Right ventricular failure
时间窗: First 24 hours post cardiac surgery
Pulmonary complications
时间窗: 30 days
Composite outcome : pneumonia, prolonged mechanical ventilation (more than 24 hours) or clinically significant atelectasis (requiring \> 2L O2).
Acute Renal failure
时间窗: 30 days
KDIGO : class I and more
次要结局
- Maximal blood lactate levels(First 24h)
- Fluid balance(First 24h)
研究者
Andre Denault
MD PhD FRCPC ABIM-CCM
Montreal Heart Institute