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Clinical Trials/NCT06505213
NCT06505213
Not yet recruiting
Not Applicable

Multimodal Brain Monitoring as an Early Warning and Prognostic Tool for Acute Brain Injury

Xiangya Hospital of Central South University0 sites490 target enrollmentJuly 30, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Brain Injury
Sponsor
Xiangya Hospital of Central South University
Enrollment
490
Primary Endpoint
Relation between multimodal brain monitoring parameters and outcome.
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

The primary aim of this study is to evaluate the effectiveness of multimodal brain monitoring technologies as both an early warning system and a prognostic tool in patients suffering from acute brain injuries. This research seeks to determine how effectively these tools can predict clinical outcomes and prevent complications by providing early alerts to healthcare professionals.

Detailed Description

Acute brain injury, including traumatic brain injury (TBI) and stroke, presents significant challenges in clinical management, primarily due to the complexity of the brain's response to injury and the critical timing required for effective intervention. Multimodal brain monitoring, which integrates various physiological data points like brain electrical activity, cerebral blood flow, and brain tissue oxygenation, offers a comprehensive view of a patient's cerebral status. This study builds on the premise that a better understanding and real-time monitoring of these variables can significantly improve patient outcomes by enabling timely and targeted interventions.

Registry
clinicaltrials.gov
Start Date
July 30, 2024
End Date
June 30, 2028
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Xiangya Hospital of Central South University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Relation between multimodal brain monitoring parameters and outcome.

Time Frame: 6 months

Association between advanced multimodal brain monitoring parameters of the first 48h of admission and six months functional outcome (Glasgow Outcome Score Extended)

Secondary Outcomes

  • Neuromonitoring Pattern(3-5 days)
  • Neuromonitoring and Short Term Outcome(28 days)

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