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Clinical Trials/NCT06246500
NCT06246500
Terminated
Not Applicable

Severe Head Trauma: Coagulation and CT-Scan Aggravation.

Centre Hospitalier Annecy Genevois1 site in 1 country23 target enrollmentMay 11, 2021
ConditionsHead Trauma

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Head Trauma
Sponsor
Centre Hospitalier Annecy Genevois
Enrollment
23
Locations
1
Primary Endpoint
Describe the evolution of CT scan lesions between admission and reassessment CT scan
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

Retrospective, multicenter cohort study describing the biological, radiological and clinical criteria of patients managed for isolated severe head trauma between January 2016 and December 2018.

Detailed Description

The objective of the study is to describe the evolution of CTscan lesions in patients with isolated Head Trauma between admission and re-evaluation after 24 hours.

Registry
clinicaltrials.gov
Start Date
May 11, 2021
End Date
July 8, 2021
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients informed and did not object to the collection of their medical data for the study
  • Patient admitted in Trauma center between January 2016 and December 2018 severe head injury defined by a Glasgow Coma Scale (GCS) \< 9 AND/OR Abnormalities on the first brain CT-scan with pathological transcranial Doppler (Vd \< 25 cm/s and IP \> 1.25)

Exclusion Criteria

  • Abbreviated Injury Score (AIS) head and neck ≤ 3 AND/OR AIS out of head and neck \> 3
  • Taking drugs that interfere with hemostasis, such as anticoagulant or antiplatelet antiaggregants in preventive or curative doses;
  • Patients under guardianship
  • Patients still alive at the time of data collection AND opposed to the collection of their data

Outcomes

Primary Outcomes

Describe the evolution of CT scan lesions between admission and reassessment CT scan

Time Frame: 24 hours

Number of patient with an aggravation of lesions on CT scan

Secondary Outcomes

  • Mortality(Day 28)
  • Causes of death(Day 28)
  • Describe the coagulation status on admission with severe head trauma trauma(24 hours)

Study Sites (1)

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