Prognosis Analysis of Elderly Donor Liver From Donation After Cardiac Death in Liver Transplantation: a Multicenter Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11,569
- 主要终点
- Transplanted liver status
研究概览
简要总结
Based on the follow-up data of elderly donation after cardiac death(DCD) donor liver transplant recipients from the CLTR, a database and official website for national data gathering. patients who met the enrollment criteria were screened for postoperative complications and survival for statistical analysis to understand the prognosis of patients and analyze the risk factors affecting their prognosis.
详细描述
Since the Chinese organ donation system was developed in 2015, donation has been the only source of organs for transplantation in China. Adult patients (age 18 or older) who underwent LT using grafts from deceased donors between January 1st, 2015, and December 31st, 2018, were retrospectively identified using the CLTR, a database and official website for national data gathering. Based on the follow-up data of elderly DCD donor liver transplant recipients from the CLTR, a database and official website for national data gathering. patients who met the enrollment criteria were screened for postoperative complications and survival for statistical analysis to understand the prognosis of patients and analyze the risk factors affecting their prognosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recipient age ≥ 18 years and < 65 years.
- •Donor age ≥ 18 years.
排除标准
- •Recipient age <18 years or ≥65 years.
- •Donor age <18 years.
- •Patients who died within 30 days after transplantation.
- •Secondary liver transplantation.
- •Multiple organ transplantation.
- •Patients with incomplete data or failed follow-up.
结局指标
主要结局
Transplanted liver status
时间窗: Time from the end of liver transplantation to the patient's death, or the end of follow-up by December 31, 2020. whichever came first, assessed up to 72 months.The functional status of the transplanted liver was recorded during this period.
Postoperative Liver Function in Patients Undergoing Liver Transplantation
Recurrence of the primary disease after surgery
时间窗: The time period between liver transplantation and the initial examination revealing a recurrence of primary disease, or until the end of follow-up on December 31, 2020.whichever came first, assessed up to 72 months.
Recurrence of primary disease in patients who underwent liver transplantation after surgery
Post-operative survival time
时间窗: Time from the end of liver transplantation to the patient's death, or the end of follow-up by December 31, 2020. whichever came first, assessed up to 72 months.
Postoperative survival time for patients receiving liver transplantation
次要结局
- Post-operative complications in patients who underwent liver transplantation(Time from the end of liver transplantation to the patient's death, or the end of follow-up by December 31, 2020. whichever came first, assessed up to 72 months.During this period, all postoperative complications of the patient will be recorded.)
- Surgery details(Intraoperative)
研究者
Hu Liangshuo
Principal Investigator
First Affiliated Hospital Xi'an Jiaotong University