Comparison of three protective regimens for preventing contrast-induced nephropathy in high risk patients undergoing coronary angiography

Qom University of Medical Sciences and Health Services0 个研究点目标入组 147 人开始时间: 待定最近更新: 2018年2月22日

适应症

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•Patients, who have at least one of the following risk factors: 1) Age>65 years, 2) Diabetes mellitus, 3) Heart failure (25%>ejection fraction>40%), 4) Renal insufficiency (creatinine³1.5mg/dl), 5) Control hypertension (systolic and diastolic blood pressure <160 mm Hg and < 100 mm Hg, respectively), 6) Recent use of NSAID’S, ACE inhibitor and amino glycosides drugs. Exclusion criteria : 1) Pregnancy & lactation, 2) Allergy to radiographic contras,t 3) Have of cardogenic shock, pulmonary edema, multiple myeloma, pulmonary ventilation and emergency catheterization 4) Serum creatinine levels< 4 mg/dL and preexisting dialysis 5) Exposure to contrast medium within the preceding 48 hours of the study, 6) Receive of diuretics, N-acetylcystein, sodium bicarbonate, theophylline, dopamine, mannitol, fenoldopam, metformin and NSAID’S during the study period. 7) Need for continuous hydration therapy (e.g., sepsis), 8) Uncontrolled hypertension (systolic and diastolic blood pressure >160 mm Hg and >100 mm Hg, respectively)

发起方

Qom University of Medical Sciences and Health Services