Botulinum toxin injection for vocal cord dysfunction in asthma

Not Applicable

Completed

• Conditions: Asthma; Vocal cord dysfunction; Respiratory - Asthma

• Registration Number: ACTRN12613000455763
• Lead Sponsor: Monash Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Difficult-to-treat asthma unresponsive to optimised treatments,
Vocal cord dysfunction on imaging,
ACT score <15

Exclusion Criteria

Allergy to botulinum toxin
Other known laryngeal disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Asthma Control Test Score one month after injection.[One month];Degree of vocal cord dysfunction detected on Computerised Tomography (CT) imaging of the larynx after one month.[One month]

Secondary Outcome Measures

Name	Time	Method
Side efftects immediately after injection, formally after one month and after 3 months. This entailed a history of known possible side-effects (loss of voice, dysphagia, choking, cough) as well as any spontaneous adverse symptoms.[Three months]