Study on the characteristic spectrum of sleep related factors in patients with insomnia diagnosed by single chief complaint of Wushen type

Phase 1

Recruiting

• Conditions: insomnia

• Registration Number: ITMCTR2100004655
• Lead Sponsor: Ttraditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Inclusion criteria of healthy control (the following four items should be met simultaneously):
(1) They are between 20 and 60 years old, including those aged 20 and 60 years.
(2) Healthy without disease.
(3) The age, gender and ethnic characteristics of the patients were the same as those of the other groups.
(4) Informed consent, volunteers, signed informed consent.
2. The inclusion criteria of TCM insomnia five spirit classification (the following five items should be met at the same time):
(1) All the cases met the diagnostic criteria of traditional Chinese and Western Medicine (see above).
(2) Pittsburgh sleep quality index (PSQI) score >= 8.
(3) They are between 20 and 60 years old, including those aged 20 and 60 years.
(4) The six groups were comparable in age, gender and ethnic characteristics.
(5) Informed consent, volunteers, signed informed consent.

Exclusion Criteria

1. Exclusion criteria for healthy control: those who conceal their health, age, gender and voluntary status.
2. Exclusion criteria for the study of insomnia five spirit classification in traditional Chinese Medicine
(1) Among the five types of chief complaint symptoms, it is difficult to select the single chief complaint symptom or the single chief complaint symptom is not prominent.
(2) Pregnant and lactating women.
(3) Insomnia caused by drinking and taking central stimulant drugs.
(4) Insomnia caused by physical and mental diseases.
(5) Use of psychotropic drugs or not discontinued for more than two weeks
(6) Heart, brain, kidney, liver and other serious diseases..
(7) Patients with epilepsy.
(8) Poor compliance of scientific research and incomplete data.

Study & Design

• Study Type: Observational study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Corticotropin releasing hormone;GABA;leptin;Adrenocorticotropic hormone;T3;Norepinephrine;IL-6;histamine;5-hydroxyindoleacetic acid;melatonin;GAD;IL=1;glycine;Hydrocortisone;T4;testosterone;VIP;acetylcholine;DA;glutamate;Gonadotropin releasing hormone;Thyroid stimulating hormone releasing hormone;5-HT;Estradiol;Apolipoprotein;Orexin A;