The Assessment of Knee Joints Function in People After Stroke

Completed

• Conditions: Stroke

• Registration Number: NCT06746493
• Lead Sponsor: Poznan University of Medical Sciences

Brief Summary

The study aims to assess the function of knee joints in patients after stroke compared to healthy people and evaluate the impact of rehabilitation on the function of knee joints in people after stroke.

Detailed Description

Stroke patients were examined twice at the beginning of rehabilitation and after approximately 15 days of exercise. The control group (healthy participants) was assessed once. Wireless motion sensors connected to a mobile application were used to assess the kinematics of the knee joints. They were used to assess the range of motion in the knee joints (passive, active, active at maximum speed), proprioception (joint position sense tests), step-up test, step-down test, getting up and sitting on a chair, step and squat. Functional tests such as The Five Times Sit-to-Stand Test, Timed Up\&Go, The Step Test, the 5m walking test, and the 30-s Chair Stand Test were carried out. The strength of the knee extensors and flexors was also assessed using the Leg Force Feedback device. Balance was assessed on a posturography platform by performing tests such as standing with eyes open and closed on a stable surface and standing with eyes open and closed on an unstable surface. The symmetry of lower limb loads in a standing position was also assessed.

Study Timeline

• Study Start: 2021-11-10
• Primary Completion: 2022-04-07
• Study Completion: 2022-06-15
• Study First Submitted: 2024-03-11
• Status Verified: 2024-12
• Study First Submitted QC: 2024-12-20
• Last Update Submitted: 2024-12-23
• Study First Posted: 2024-12-24
• Last Update Posted: 2024-12-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of the passive and active range of motion of the knee joint using wireless motion sensors connected to a mobile application.	Baseline and after about 15 days of exercise.	Measurement of the passive and active range of motion of the knee joint in degrees in lying position using wireless motion sensors connected to a mobile application.
Proprioception	Baseline and after about 15 days of exercise.	Assessment of joint position sensation (3 different positions indicated) in degrees using wireless sensors.
Assessment of the active range of motion of the knee and hip joint during functional tasks	Baseline and after about 15 days of exercise.	Measurement of the range of motion of the knee and hip joint using wireless motion sensors connected to a mobile application during functional tasks such as: step up, step down, squat, sitting on a chair and getting up from a chair and step forward.
Assessment of the maximum angle of varus and valgus at the knee joint during functional tasks	Baseline and after about 15 days of exercise.	Measurement of the maximum angle of varus and valgus at the knee joint using wireless motion sensors connected to a mobile application during functional tasks such as: step up, step down, squat, sitting on a chair and getting up from a chair and step forward.
Assessment of the mean squared error at the knee joint during functional tasks	Baseline and after about 15 days of exercise.	Measurement of the mean squared error using wireless motion sensors connected to a mobile application during active flexion and extension motion in the knee joint at maximum speed and functional tasks such as: step up, step down, squat, sitting on a chair and getting up from a chair and step forward.
Assessment of the speed of movement in the knee joint during functional tasks	Baseline and after about 15 days of exercise.	Measurement of the speed of movement in the knee joint during active flexion and extension motion in the knee joint at maximum speed and functional tasks such as: squat and sitting on a chair and getting up from a chair.
Step test	Baseline and after about 15 days of exercise.	Assessment of the number of repetitions.
The Five Times Sit-to-Stand Test	Baseline and after about 15 days of exercise.	Assessment of task completion time.
Timed Up&Go Test	Baseline and after about 15 days of exercise.	Assessment of task completion time.
30-s Chair Stand Test	Baseline and after about 15 days of exercise.	Assessment of the number of repetitions.
5m walking test	Baseline and after about 15 days of exercise.	Assessment of task completion time.
Assessment of isometric muscle strength of knee flexors and extensors using Leg Force Feedback device.	Baseline and after about 15 days of exercise.	Measurement of the maximal voluntary isometric contraction torque of the knee extensor and flexor muscle groups in Newton-meter.
Symmetry	Baseline and after about 15 days of exercise.	Assessment of the load on the lower limbs while standing in percentage.

Secondary Outcome Measures

Name	Time	Method
Assessment of the center of pressure path length when measuring on a balance platform	Baseline and after about 15 days of exercise.	Measurement of parameter such as total path length (cm). A test was performed in four conditions: standing with eyes open and closed on a stable surface and standing with eyes open and closed on an unstable surface.
Assessment of the center of pressure velocity when measuring on a balance platform	Baseline and after about 15 days of exercise.	Assessment of parameter such as average speed (cm/s). A test was performed in four conditions: standing with eyes open and closed on a stable surface and standing with eyes open and closed on an unstable surface.
Balance	Baseline and after about 15 days of exercise.	The test was performed in four conditions: standing with eyes open and closed on a stable surface and standing with eyes open and closed on an unstable surface. The results were obtained in percentage values and compared to the normative results from the system.

Trial Locations

Locations (1)

Poznan University of Medical Sciences; 🇵🇱 Poznań, Poland