Inflammatory markers for prognosis of sepsis and septic shock

Not yet recruiting

• Conditions: Sepsis, unspecified organism,

• Registration Number: CTRI/2021/09/036242
• Lead Sponsor: Dr B L Kapur Memorial Hospital

Brief Summary

Aim: A qualitative evaluation of PCT,CRP IL-6 for prognosis of sepsis and septic shock

Primary objective: Prognostic value of PCT,CRP and IL-6 in patients with sepsis and septic shock.



Secondary objective: To assess the correlation of  PCT,CRP and IL-6 with disease severity scoring system- APACHE II and SOFA

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-03-09
• Study Start: 2021-07-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Patients admitted in Medical ICU with a suspected diagnosis of Sepsis and Septic Shock, with likely stay >72 hours.

Exclusion Criteria

• 1.Patients undergoing any emergency surgery.
• Patients with a diagnosis of cancer or undergoing therapy for cancer.
• Pregnant patients 4.
• Extremely critical patients: Refractory shock, Severe refractory metabolic acidosis (pH<7.0), persistent hypoxemia (PaO2 (<50 mm Hg), Multiorgan failure on presentation (3 or more organ failures on presentation), APACHE II >35, SOFA>20.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prognostic value of Procalcitonin (PCT), C-Reactive Protein (CRP) and	Day 1,Day 3,Day 7 and day 12
Interleukin-6 (IL-6) in patients with sepsis and septic shock	Day 1,Day 3,Day 7 and day 12

Secondary Outcome Measures

Name	Time	Method
To assess correlation Procalcitonin (PCT), C-Reactive Protein (CRP) and	Interleukin-6 (IL-6) with disease severity scoring systems- Acute

Trial Locations

Locations (1)

Dr.B.L Kapur Memorial Hospital; 🇮🇳 Delhi, DELHI, India

Dr.B.L Kapur Memorial Hospital

🇮🇳Delhi, DELHI, India

Dr Vishal Upadhyay

Principal investigator

8447927104

dr.vishalupadhyay@yahoo.com