Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage
Completed
- Conditions
- Anastomotic Leakage in Colon Surgery
- Interventions
- Procedure: Colon surgery
- Registration Number
- NCT02361918
- Lead Sponsor
- Istanbul University
- Brief Summary
Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.
- Detailed Description
To search for a biomarker, which might be able to predict rectal anastomotic leakage before its clinical presentation. Serum procalcitonin, C-reactive protein, and drain fluid culture, IL-6 and TNF-α levels were evaluated in 50 consecutive patients with rectal cancer who underwent low anterior resection with colorectal anastomosis.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Patient underwent to colonic resection and had drain
Exclusion Criteria
- other patients
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Anastomotic leakage Colon surgery Patient had anastomotic leakage No anastomotic leakage Colon surgery Patient had no anastomotic leakage
- Primary Outcome Measures
Name Time Method Predictive values of serum CRP, procalcitonin, drain fluid IL-6 and TNF-alpha levels in anastomotic leakage. 5 day
- Secondary Outcome Measures
Name Time Method