Research of Serum Procalcitonin, Erythrocyte Sedimentation Rate, C-Reactive Protein And Leukocyte Levels in Fertile Missed Abortion Cases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Serum LC
研究概览
简要总结
Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion
详细描述
The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease
排除标准
- •Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)
- •Rejection to participate in the study.
结局指标
主要结局
Serum LC
时间窗: 01.01.2018- 15.02.2019
Serum leukocyte count in number
ESR
时间窗: 01.01.2018- 15.02.2019
Erythrocyte sedimentation rate
CRP
时间窗: 01.01.2018- 15.02.2019
Serum CRP level in microgram
Prokalsitonin
时间窗: 01.01.2018- 15.02.2019
Serum procalcitonin level in microgram
次要结局
未报告次要终点
研究者
Suleyman Guven
Clinical Professor.
Karadeniz Technical University
