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临床试验/NCT03767179
NCT03767179已完成不适用

Research of Serum Procalcitonin, Erythrocyte Sedimentation Rate, C-Reactive Protein And Leukocyte Levels in Fertile Missed Abortion Cases

Karadeniz Technical University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2018年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
1
主要终点
Serum LC

研究概览

简要总结

Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion

详细描述

The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease

排除标准

  • Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)
  • Rejection to participate in the study.

结局指标

主要结局

Serum LC

时间窗: 01.01.2018- 15.02.2019

Serum leukocyte count in number

ESR

时间窗: 01.01.2018- 15.02.2019

Erythrocyte sedimentation rate

CRP

时间窗: 01.01.2018- 15.02.2019

Serum CRP level in microgram

Prokalsitonin

时间窗: 01.01.2018- 15.02.2019

Serum procalcitonin level in microgram

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Suleyman Guven

Clinical Professor.

Karadeniz Technical University

研究点 (1)

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