Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases
- Conditions
- Abortion, Missed
- Interventions
- Diagnostic Test: study
- Registration Number
- NCT03767179
- Lead Sponsor
- Karadeniz Technical University
- Brief Summary
Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion
- Detailed Description
The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 60
- fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease
- Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)
- Smoking
- Rejection to participate in the study.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Study Group study The study group consisted of 30 fertile, under 35 years old women who were included in the study for the first time missed abortus diagnosis. Control Group study 30 cases with the same trimester, fertile, and under 35 years old who were referred to Obstetrics clinic, who had no systemic disease, were included in the study.
- Primary Outcome Measures
Name Time Method Serum LC 01.01.2018- 15.02.2019 Serum leukocyte count in number
ESR 01.01.2018- 15.02.2019 Erythrocyte sedimentation rate
CRP 01.01.2018- 15.02.2019 Serum CRP level in microgram
Prokalsitonin 01.01.2018- 15.02.2019 Serum procalcitonin level in microgram
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Karadeniz Technical University, Medical Faculty of Medicine.
🇹🇷Trabzon, Ortahisar, Turkey