CTRI/2010/091/001227未知不适用
To compare the effect of nebulised 3% hypertonic saline (HS) with nebulised 0.9% normal saline in treatment of bronchiolitis in hospitalized children by a hospital based randomized, double-blind control trial.?
适应症
试验速览
- 阶段
- 不适用
- 发起方
- self
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- imrovement in psi score
研究概览
简要总结
this study is randomised, double blind, conrolled trial comparing hypertonic saline verses normal saline in treatment of bronchiolitis in moderately ill hospitalised children. primary outcome measured will be improvement in psi score and secondary outcome will be reduction in hospital stay.
研究设计
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
入选标准
- •Children with bronchiolitis (defined by prodrome of upper respiratory tract infection, including rhinorrhea, cough, and sometimes low-grade fever, which progresses to lower respiratory tract involvement, paroxysmal cough and dyspnoea), with pulmonary score index >0 and ≤ 6.
排除标准
- •previous episode of wheezing; chronic cardiopulmonary disease; critical illness at presentation requiring admission to intensive care; or ventilatory support;the use of nebulised HS within the previous 12 hours;pulmonary score index > 6;.
结局指标
主要结局
imrovement in psi score
时间窗: when psi score less than 3
次要结局
- reduction in hospital stay(time taken to achieve study end points)
研究者
研究点 (1)
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