hypertonic saline in bronchiolitis

• Conditions: bronchiolitis

• Registration Number: CTRI/2010/091/001227
• Lead Sponsor: self

Brief Summary

this study is randomised, double blind, conrolled trial comparing hypertonic saline verses normal saline in treatment of bronchiolitis in moderately ill hospitalised children. primary outcome measured will be improvement in psi score and secondary outcome will be reduction in hospital stay.

Detailed Description

Not available

Recruitment & Eligibility

• Sex: Not specified
• Target Recruitment: 250

Inclusion Criteria

Children with bronchiolitis (defined by prodrome of upper respiratory tract infection, including rhinorrhea, cough, and sometimes low-grade fever, which progresses to lower respiratory tract involvement, paroxysmal cough and dyspnoea), with pulmonary score index >0 and ≤ 6.

Exclusion Criteria

previous episode of wheezing; chronic cardiopulmonary disease; critical illness at presentation requiring admission to intensive care; or ventilatory support;the use of nebulised HS within the previous 12 hours;pulmonary score index > 6;.

Study & Design

• Study Type: Not specified
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
imrovement in psi score	when psi score less than 3

Secondary Outcome Measures

Name	Time	Method
reduction in hospital stay	time taken to achieve study end points

Trial Locations

Locations (1)

s ms hospital japur; 🇮🇳 Jaipur, RAJASTHAN, India

s ms hospital japur

🇮🇳Jaipur, RAJASTHAN, India

dr B. S. Sharma

Principal investigator

drbssharma@gmail.com