Baduanjin Exercising Effects on Sub-clinical Hypothyroidism and Cognitive Problems

Not Applicable

Recruiting

• Conditions: Cognitive Impairment; Subclinical hypothyroïdism
• Interventions: Behavioral: Baduanjin exercising

• Registration Number: NCT05803967
• Lead Sponsor: Cairo University

Brief Summary

Females with sub-clinical hypothyroidism may exhibit frequent cognitive problems especially if they are elderly

Detailed Description

Females (forty in number) with sub-clinical hypothyroidism exhibit cognitive problems, they are elderly, will be divided to exercised group (baduanjin training will be applied 5 times per the week, under supervision for 12 weeks, number of patients will be 20) and other non exercised group (number of patients will be 20) . all women of groups will received their prescribed daily one-dose medication tablet (levothyroxine).

Study Timeline

• Study Start: 2022-12-18
• Status Verified: 2023-03
• Study First Submitted: 2023-03-27
• Study First Submitted QC: 2023-03-27
• Last Update Submitted: 2023-03-27
• Study First Posted: 2023-04-07
• Last Update Posted: 2023-04-07
• Primary Completion: 2023-06-18
• Study Completion: 2023-06-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• female with sub-clinical hypothyroidism
• females with mild cognitive impairment
• females with obesity (obesity class one)

Exclusion Criteria

• neurological problems
• orthopedic problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group number 1	Baduanjin exercising	Females with sub-clinical hypothyroidism exhibit cognitive problems (mild cognitive impairement), they will be elderly, will receive baduanjin training that will be applied 5 times per the week, under supervision for 12 weeks, number of patients will be 20), also women of this group will receive their prescribed daily one-dose medication tablet (levothyroxine).

Primary Outcome Measures

Name	Time	Method
thyroid stimulating hormone	it will be measured after 12 weeks	will be measured in serum of women with hypothyroidism

Secondary Outcome Measures

Name	Time	Method
triglycerides	it will be measured after 12 weeks	will be measured in serum of women with hypothyroidism
systolic blood pressure	it will be measured after 12 weeks	will be measured by manual sphygmomanometer
Addenbrooke Cognitive Examination	it will be measured after 12 weeks	will assess Cognitive impairment
diastolic blood pressure	it will be measured after 12 weeks	will be measured by manual sphygmomanometer
low density lipoprotein	it will be measured after 12 weeks	will be measured in serum of women with hypothyroidism
cholesterol	it will be measured after 12 weeks	will be measured in serum of women with hypothyroidism
high density lipoprotein	it will be measured after 12 weeks	will be measured in serum of women with hypothyroidism
body mass index	it will be measured after 12 weeks	it will be measure on empty bladder and stomach

Trial Locations

Locations (1)

Cairo Unoversity; 🇪🇬 Giza, Egypt