A Dietary Intervention to Modify Breast Milk Content in Obese Lactating Women
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Effect of Diet on Breast Milk Composition
- Sponsor
- Arkansas Children's Hospital Research Institute
- Enrollment
- 32
- Locations
- 1
- Primary Endpoint
- Change in breast milk fat concentration by mid-infrared spectroscopy
- Status
- Completed
- Last Updated
- 7 months ago
Overview
Brief Summary
This study is a nutrition research study designed to look at how healthy meals can influence the content of breast milk. Moms will be provided with meals that follow a Mediterranean diet pattern for 4 weeks. The goal of the study is to see if breast milk content changes over the 4 week period. The infants of the moms will also be included in the study to measure any changes in growth.
Investigators
Eligibility Criteria
Inclusion Criteria
- •≤4.5 months postpartum
- •BMI 30 - 50 kg/m2
- •≥ 18 years of age
- •Singleton pregnancy
- •Exclusive breastfeeding and plans to exclusively breastfeed for at least 6 months postpartum
- •Mother has a breast pump
- •Mother is willing to collect breast milk for a 24 hour period.
Exclusion Criteria
- •Pre-existing conditions (e.g. diabetes, hypertension, heart disease)
- •Use of recreational drugs, tobacco, or alcohol
- •Use of medications or supplements for which breastfeeding is contraindicated
- •Child has internal metal which may be an NMR safety concern
Outcomes
Primary Outcomes
Change in breast milk fat concentration by mid-infrared spectroscopy
Time Frame: The change in breast milk fat concentration will be assessed by mid-infrared spectroscopy by measuring the concentration before the participants begin the dietary intervention, 2 weeks into the intervention, and at the end of the 4-week intervention.
The primary aim is to test whether the dietary intervention modifies the breast milk fat concentration of obese mothers.