Laparoscopic Assisted Pull-through Versus Other Surgical Procedures for Treatment of Hirschsprung Disease.
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- Constipation
研究概览
简要总结
To evaluate the outcomes of laparoscopic pull-through concerning constipation, incontinence and enterocolitis in comparison of other surgical procedures for treatment of Hirschsprung disease.
详细描述
Hirschsprung,s disease (HD) is a relatively common cause of intestinal obstruction in the newborn[1,2], The main goal in the treatment of patients with Hirschsprung,s disease is to resect the aganglionic segment and pull down the Normo-ganglionic bowel[3]. With the introduction of minimally invasive surgery, classic pull-through techniques were modified and improved with laparoscopy, because of the obvious advantages of laparoscopic-assisted pull-through operations in form of reduced pain and improved cosmoses this approach has gained much popularity[4,5].
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Months 至 36 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 6months to 3 years.
- •Both sexes.
- •Classic and long segment Hirshsprung.
- •Total a ganglionic colon.
- •Hirshsprung disease with leveling colostomy
排除标准
- •Patients <6 months and >3 years.
- •Short and Ultra-short Hirshsprung.
- •Recurrent cases of Hirshsprung.
- •Other contraindication of laparoscopy
研究组 & 干预措施
laparoscopic operated group
Under general anesthesia and insertion of ports for laparoscopic instruments, laparoscopic assisted mobilization of sigmoid colon and dissection till pelvis and removal of a ganglionic segment of colon and laparoscopic assisted pull through of colon then colo-anal anastomosis will be done,
干预措施: laparoscopic assisted pull-through oeration (Procedure)
non laparoscopic operated group
Under general anesthesia ,abdominal exploration ,removal of a ganglionic part by soav ,duhamel procedures and trans-anal pull through procedures.
干预措施: laparoscopic assisted pull-through oeration (Procedure)
结局指标
主要结局
Constipation
时间窗: from one to three months after operation
persistace of inablilty to pass stool even after operation and treatment,it is physiological parameter and assisted by asking the mothers of patients about the bowel habits.
次要结局
未报告次要终点
研究者
Mohammed Hamada Takrouney
Principal investigator and Assistant lecturer of pediatric surgery
Assiut University