Laparoscopic Assisted Pull-through Versus Other Surgical Procedures for Treatment of Hirschsprung Disease

Not Applicable

• Conditions: Hirschsprung Disease
• Interventions: Procedure: laparoscopic assisted pull-through oeration

• Registration Number: NCT03269812
• Lead Sponsor: Assiut University

Brief Summary

To evaluate the outcomes of laparoscopic pull-through concerning constipation, incontinence and enterocolitis in comparison of other surgical procedures for treatment of Hirschsprung disease.

Detailed Description

Hirschsprung,s disease (HD) is a relatively common cause of intestinal obstruction in the newborn\[1,2\], The main goal in the treatment of patients with Hirschsprung,s disease is to resect the aganglionic segment and pull down the Normo-ganglionic bowel\[3\]. With the introduction of minimally invasive surgery, classic pull-through techniques were modified and improved with laparoscopy, because of the obvious advantages of laparoscopic-assisted pull-through operations in form of reduced pain and improved cosmoses this approach has gained much popularity\[4,5\].

Study Timeline

• Status Verified: 2017-08
• Study First Submitted: 2017-08-29
• Study First Submitted QC: 2017-08-30
• Last Update Submitted: 2017-08-30
• Study Start: 2017-09-01
• Study First Posted: 2017-09-01
• Last Update Posted: 2017-09-01
• Primary Completion: 2019-09-01
• Study Completion: 2019-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Age from 6months to 3 years.
2. Both sexes.
3. Classic and long segment Hirshsprung.
4. Total a ganglionic colon.
5. Hirshsprung disease with leveling colostomy

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Exclusion Criteria

1. Patients <6 months and >3 years.
2. Short and Ultra-short Hirshsprung.
3. Recurrent cases of Hirshsprung.
4. Other contraindication of laparoscopy

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
laparoscopic operated group	laparoscopic assisted pull-through oeration	Under general anesthesia and insertion of ports for laparoscopic instruments, laparoscopic assisted mobilization of sigmoid colon and dissection till pelvis and removal of a ganglionic segment of colon and laparoscopic assisted pull through of colon then colo-anal anastomosis will be done,
non laparoscopic operated group	laparoscopic assisted pull-through oeration	Under general anesthesia ,abdominal exploration ,removal of a ganglionic part by soav ,duhamel procedures and trans-anal pull through procedures.

Primary Outcome Measures

Name	Time	Method
Constipation	from one to three months after operation	persistace of inablilty to pass stool even after operation and treatment,it is physiological parameter and assisted by asking the mothers of patients about the bowel habits.