To study the effect of injection Bupivacaine(0.25%) into abdominal cavity for postoperative pain relief following Laparoscopic cholecystectomy

Brief Summary: My Thesis is to study the effect of instillation of intraperitoneal Bupivacaine (0.25%) to achieve postoperative analgesia in 50 patients undergoing Laparoscopic Cholecystectomy. Patients belonging to ASA grade I-II, aged 18year to 60years, weighing between 45-85 Kgs, undergoing Laparoscopic Cholecystectomy under General Anaesthesia are selected for the study.

After removal of gallbladder and haemostasis achieved, residual blood and fluid will be thoroughly suctioned. The surgeon will instill 40ml of 0.25% Bupivacaine in the subdiaphragmatic suprahepatic surface of liver and gall bladder. In the postoperative period, we observe the duration of analgesia using Visual Analog Score, hemodynamic variables, 24 hours analgesic requirement, and any side effects.

Recruitment & Eligibility

Inclusion Criteria

ASA grade I-II Age 18 â€“ 60 years Weight 45-85Kg A patient undergoing Laparoscopic Cholecystectomy under General Anaesthesia.

Exclusion Criteria

Needing bile duct exploration, insertion of a T-drain.
Acute cholecystitis.
Surgery-related complication example, bile spillage or conversion to open cholecystectomy Duration of surgery exceeded 2 hours.
Severe systemic disease.
Prolong Analgesics ingestion Allergy to local anesthetics.

Primary Outcome Measures

Name	Time	Method
Proportion of patients having Visual Analog Score(VAS)3 at 3hours	Proportion of patients having Visual Analog Score(VAS)3 at 3hours

Secondary Outcome Measures

Name	Time	Method
Duration of analgesia	Haemodynamic Variables such as Heart Rate (HR), Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP)

Locations (1): Pt J N M Medical College and Dr B R A M hospital, Raipur
🇮🇳
Raipur, CHHATTISGARH, India
Pt J N M Medical College and Dr B R A M hospital, Raipur
🇮🇳Raipur, CHHATTISGARH, India
Dr Avinash Banjare
Principal investigator
8120507490
banjare.avinash@gmail.com