The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis
- Conditions
- Alveolar Osteitis
- Interventions
- Other: No collagen sponge application after surgical extraction of impacted 3rd molarOther: Application of a collagen sponge after surgical extraction of impacted 3rd molar
- Registration Number
- NCT05850650
- Lead Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
- Brief Summary
The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures. Collagen plugs will be applied in the sockets of the study side followed by suture, while the controlled side will be sutured without a collagen plug. The study will include 40 patients aged between 18- 40 years old, medically fit (ASA1), who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction. The main question is" Does intra-alveolar collagen application after surgical extraction of impacted lower third molars reduce the incidence of alveolar osteitis?
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 40
Forty patients aged between 18- 40 years old, ASA1, who have bilateral symmetrical impacted lower third molars and visit the oral surgery clinics of King Saud Medical City for extraction.
Uncontrolled systemic diseases, diabetes, bone diseases, smokers, epinephrine contraindications, pregnant women, breastfeeding women, and those who were using oral contraceptives.
Other exclusion criteria are the presence of acute infection and facial swelling, cystic lesions, and TMJ problems. Moreover, any surgical extraction that lasts more than 30 minutes +/- 5 minutes, or has been done without the whole standardized steps will be excluded.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Controlled No collagen sponge application after surgical extraction of impacted 3rd molar The extraction socket will not receive a collagen sponge Collagen Application of a collagen sponge after surgical extraction of impacted 3rd molar The extraction socket will receive a collagen sponge
- Primary Outcome Measures
Name Time Method Pre-extraction Pain score Pre-extraction Pain measurement by VAS (0-10). 0: no pain. 10: worst pain
Pain score Day3 3 days after extraction Pain measurement by VAS (0-10). 0: no pain. 10: worst pain
Halitosis Day7 7 days after extraction Halitosis in reported in the presence of a bad odor that is smelled by the investigator during the patient's speech
Pre-extraction Halitosis Pre-extraction Halitosis in reported in the presence of a bad odor that is smelled by the investigator during the patient's speech
Pre-extraction Mouth opening Pre-extraction Maximum Mouth opening is taken by a caliber
Mouth opening Day7 7 days after extraction Maximum Mouth opening is taken by a caliber
Alveolar osteitis After 3 days of extraction is diagnosed if the patient complains of pain (more than 5) between day 2 and day 4 with empty sockets and food debris, with or without halitosis
Pain score Day7 7 days after extraction Pain measurement by VAS (0-10). 0: no pain. 10: worst pain
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
RiyadH Colleges of dentistry and Pharmacy
🇸🇦Riyadh, Saudi Arabia