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Clinical Trials/NCT03445819
NCT03445819
Unknown
N/A

A Prospective Randomized Trial of Non-operative Versus Operative Management of Patella Fractures in the Elderly

Unity Health Toronto3 sites in 1 country84 target enrollmentNovember 1, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Patella Fracture
Sponsor
Unity Health Toronto
Enrollment
84
Locations
3
Primary Endpoint
Knee injury and Osteoarthritis Outcome Score (KOOS)
Last Updated
4 years ago

Overview

Brief Summary

This is a multi-centre, randomized controlled trial comparing operative and non operative treatment for displaced patella fractures in elderly, low-demand patients.

Detailed Description

Patients with a displaced patellar fracture who meet the inclusion criteria and provide consent will be randomized to one of the two treatment arms. One group (Group A) will receive standardized non-operative treatment with immediate weight-bearing as tolerated in a knee immobilizer and early ROM exercises begun at 2 weeks post injury. The other group (Group B) will receive ORIF of their displaced patellar fracture with a standardized post-operative protocol. Post-operative rehabilitation will be standardized across both groups. Patients will be weight bearing as tolerated immediately in a removable knee immobilizer, with progressive range-of-motion exercises begun at two weeks following surgery or randomization. The knee immobilizer will be used full-time (with the exception of removal for physiotherapy and bathing) for 6 weeks after surgery or randomization. At six weeks post-treatment, patients will be allowed to perform active extension and will initiate progressive strengthening exercises of the extensor mechanism.

Registry
clinicaltrials.gov
Start Date
November 1, 2018
End Date
December 31, 2023
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Male or female patients 65 years of age or older and ambulatory prior to injury (with or without walking aids).
  • Closed fracture of the patella displaced by 5 mm or greater (Displacement will be determined by measuring the widest displacement on any x-ray view with the knee in full extension).
  • The patient scores between 3 and 6 on the Clinical Frailty Scale. This score corresponds to a low-demand patient who is ambulatory and functionally independent
  • Within 14 days of injury, the patient is able to perform a straight leg raise with less than 30 degrees of extensor lag.
  • Able to read and understand the study consent form document.
  • Willing and able to sign consent, follow the study protocol and attend follow-up visits.

Exclusion Criteria

  • Associated extremity injuries or polytrauma injuries that would otherwise require surgery or interfere substantially with rehabilitation or outcome in the opinion of the investigator.
  • Neurovascular injuries at the level of the knee requiring surgery.
  • Pathologic fractures.
  • Periprosthetic fractures, or other knee surgery which would contra-indicate inclusion in the study (e.g. previous patella ORIF or previous surgery involving patella such as patella tendon or quads repair).
  • Medical contra-indication to surgery.
  • Likely problems, in the judgment of the investigators, with maintaining follow-up (e.g. patients with no fixed address, intellectually challenged patients without adequate support, etc.).

Outcomes

Primary Outcomes

Knee injury and Osteoarthritis Outcome Score (KOOS)

Time Frame: 1 year after injury

A self-administered questionnaire that assesses five outcomes: pain, symptoms, activities of daily living, sport and recreation function, and knee-related quality of life. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.

Secondary Outcomes

  • Visual Analogue Pain Scale (VAS)(1 year after injury)
  • Range of Motion(up to 24 months)

Study Sites (3)

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