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临床试验/NCT04574310
NCT04574310已完成不适用

Evaluation of the Implantation Rate Depending on the Air Bubble Location Through Ultrasound Into the Uterine Cavity in Pre-embryo Transfer

IVI Vigo0 个研究点目标入组 400 人开始时间: 2013年9月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
400
主要终点
Implantation rate

研究概览

简要总结

The main objective of the study is to evaluate whether there is any association between the location into the uterine cavity, where the air bubbles containing the pre-embryos were placed, and the implantation rate. Therefore, the images generated during pre-embryos transfer are available in our database and studied retrospectively.

详细描述

The success of a reproductive treatment is determined by three variables: the pre-embryo quality, endometrial receptiveness and pre-embryo transfer. Several previous studies show a lack of agreement concerning the greatest measurement. For instance, some of them refer to the distance between the catheter and the uterine fundus, whereas some others take as a reference the air-bubble where the pre-embryos were placed.

It is for this reason that in the present study, we aim to evaluate the air bubble location ratio into the uterine cavity with reproductive success, taking into account the different variables to reach success. That is, embryo characteristics (quality, development day) endometrium preparation (cycle type, hormone levels on day 5) and even the transfer procedure (type of catheter, blood, difficulty channeling).

It is a study that aims to collect data from January 2013 to october 2019. To this end, the images generated during pre-embryos transfer are analyzed retrospectively. Therefore, it is evaluated the existing differences on implantation rate according to air-bubble placement into uterine cavity during the transfer procedure.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
30 Years 至 50 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Patients with normal uterine anatomy, who underwent an ultrasound guided embryo transfer.
  • BMI< 30kg/m
  • Ultrasound guided embryo transfer made by the same researcher.

排除标准

  • Presence of uterine fibroid in the anterior uterine body that make difficult the transfer visualization.
  • Asherman Syndrome.
  • Adenomyosis that reduces the uterine cavity visibility.
  • Difficult transfers where the use of a semi-rigid cannula sheath is needed to entry into the uterine cavity.
  • Previous uterine surgery that alters its anatomy.
  • Istmocele

结局指标

主要结局

Implantation rate

时间窗: Since September 2013 October 2019

Analyze Implantation rate in the groups

次要结局

未报告次要终点

研究者

发起方
IVI Vigo
申办方类型
Other
责任方
Sponsor

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