Influence of protein and creatine supplementation on the ability to perform daily living activities, quality of life and muscle structure after stroke

Phase 4

• Conditions: Stroke, not specified as haemorrhage or infarction; sarcopenia; muscle development; C10.597.613.612.500; G07.345.500.325.377.625.590

• Registration Number: RBR-9q7gg4
• Lead Sponsor: Faculdade de Medicina da Unesp de Botucatu

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-01-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

Men older than 60 years; diagnosed with ischemic stroke; with up to 24 hours of stroke; without previous disability (Modified Rankin Scale less than 1) and who agree to participate of the study.

Exclusion Criteria

Patients with hemodynamic instability; in mechanical ventilation / ICU; use of pacemaker and metal prostheses; with previous renal disease; with creatinine clearance less than 30ml / min / 1.73m²; using alternative route for feeding (nasoenteral tube / gastrostomy / parenteral nutrition); patients with allergy or intolerance to any component of the study products and those who do not agree to participate.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional capacity assessed by six-minute walk test, Timed Up and Go test and modified Rankin Scale 90 days after stroke.

Secondary Outcome Measures

Name	Time	Method
Quality of life assessed by The European 5D Quality of life Scale - EuroQol-5D 90 days after stroke.;Muscle degeneration assessed by the D3-methylhistidine marker after 7 days of intervention with creatine supplementation.