The Relationship Between Cognitive Status and Exercise Capacity, Fatigue Perception in Coronary Artery Patients

Completed

• Conditions: Coronary Artery Disease

• Registration Number: NCT06246201
• Lead Sponsor: Hacettepe University

Brief Summary

The study aimed to examine the relationship between cognitive status, exercise capacity, and fatigue perception in coronary artery disease patients.

Detailed Description

Exercise training for patients with coronary artery disease is an essential element of multicomponent cardiac rehabilitation. For the successful implementation of exercise-based cardiac rehabilitation programs, adequate cognitive function (e.g. executive function, selective attention, memory) is an important prerequisite. In patients with atherosclerotic coronary artery disease, the presence of coronary microvascular dysfunction as determined by low coronary flow reserve is associated with abnormal cerebral flow hemodynamics and mild but significant impairment in cognitive function. In the literature, there is no study examining the relationship between cognitive level and fatigue perception.

Study Timeline

• Study Start: 2023-09-01
• Study First Submitted: 2024-01-30
• Study First Submitted QC: 2024-01-30
• Status Verified: 2024-02
• Study First Posted: 2024-02-07
• Primary Completion: 2024-02-23
• Study Completion: 2024-02-23
• Last Update Submitted: 2024-02-23
• Last Update Posted: 2024-02-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Volunteering to participate in the research
• Being diagnosed with coronary artery disease
• To cooperate with the tests to be performed
• Signing a consent form

Exclusion Criteria

• Presence of neurological disease that may affect cognitive status
• Presence of clinically unstable cardiac disease
• Left ventricular ejection fraction <30%
• Being diagnosed with end-stage renal failure
• Diagnosed with active myocarditis or pericarditis
• Being diagnosed with rhythm disorder
• Having amputation, peripheral arterial disease, musculoskeletal and/or neurological diseases that will prevent participation in functional capacity tests
• Not volunteering to participate in the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive State Assessment	August 2023-August 2024	Montreal Cognitive Assessment Scale (MoCA) will be used to assess cognitive status.
Assessment of Perceived Fatigue Severity After Exercise Test	August 2023-August 2024	It will be evaluated on the Modified Borg Scale from 0 to 10. 0 means no fatigue. 10 means extremely tired.
Assessment of Exercise Capacity	August 2023-August 2024	Exercise capacity will be evaluated with modified shuttle walking test.

Secondary Outcome Measures

Name	Time	Method
Physical Activity Assessment	August 2023-August 2024	Physical activity level will be measured with the International Physical Activity Questionnaire (IPAQ). 600 METs (Metabolic Equivalent of Task) min/week means inactive.

Trial Locations

Locations (1)

Hacettepe University; 🇹🇷 Ankara, Turkey