NCT00265265已完成1 期
Phase 1, Double-Blind, Placebo-Controlled Multiple Dose Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 2
- 主要终点
- Cardiovascular responses
研究概览
简要总结
The purpose of this study is to assess potential interactions between intravenous (i.v.) cocaine and atomoxetine (Strattera) administered orally in four escalating doses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-45 years of age who are not seeking treatment at the time of the study
- •Must be able to provide written informed consent
- •Must be within 20 percent of ideal body weight and weigh at least 45 kg
- •Must meet DSM0IV diagnostic criteria for cocaine abuse or dependence
- •Must currently be using cocaine as confirmed by a positive BE
- •If female and of child bearing potential, must agree to the use of birth control
排除标准
- •please contact the site directly for more information
结局指标
主要结局
Cardiovascular responses
Safety
次要结局
- Abuse Liability
- Mood and personality assessments
- Cocaine craving
- pharmacokinetic assessment
- Psychological Effects of Cocaine
研究者
研究点 (2)
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