NCT00033059
Unknown
Phase 1
Assessment of Potential Interactions Between Intravenous Cocaine and Tolcapone
ConditionsCocaine-Related Disorders
DrugsTolcapone
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Cocaine-Related Disorders
- Sponsor
- National Institute on Drug Abuse (NIDA)
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Safety
- Last Updated
- 9 years ago
Overview
Brief Summary
The purpose of this study is to assess the potential interactions between intravenous (IV) cocaine and tolcapone.
Detailed Description
Double-blind, inpatient study by screening responses to cocaine infusions of 20 and 40 mg i.v. subjects into 1 of 2 treatment groups to assess potential interactions between i.v. cocaine infusion and treatment with tolcapone.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Volunteers dependent on cocaine and are non-treatment seeking; between 18-45 yrs of age; DSM-4 criteria for cocaine abuse or dependence
Exclusion Criteria
- •Additional criteria available during screening at the site
Outcomes
Primary Outcomes
Safety
Study Sites (1)
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