Assessment of Potential Interactions Between Intravenous Cocaine and Tolcapone

National Institute on Drug Abuse (NIDA)2 个研究点分布在 1 个国家目标入组 16 人开始时间: 2001年7月最近更新: 2017年1月11日

适应症

试验速览

阶段: 1 期
发起方: National Institute on Drug Abuse (NIDA)
入组人数: 16
试验地点: 2
主要终点: Safety

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to assess the potential interactions between intravenous (IV) cocaine and tolcapone.

详细描述

Double-blind, inpatient study by screening responses to cocaine infusions of 20 and 40 mg i.v. subjects into 1 of 2 treatment groups to assess potential interactions between i.v. cocaine infusion and treatment with tolcapone.

研究设计

研究类型: Interventional
分配方式: Randomized
主要目的: Treatment
盲法: Double

入排标准

年龄范围: 18 Years 至 45 Years（Adult）
性别: All
接受健康志愿者: 否

入选标准

•Volunteers dependent on cocaine and are non-treatment seeking; between 18-45 yrs of age; DSM-4 criteria for cocaine abuse or dependence

排除标准

•Additional criteria available during screening at the site

结局指标

主要结局

Safety

次要结局

未报告次要终点

研究者

发起方

National Institute on Drug Abuse (NIDA)

申办方类型

Nih

研究点 (2)

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