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临床试验/ISRCTN65670698
ISRCTN65670698已完成未知

Randomised, double-blind, placebo-controlled clinical trial of trimethoprim-sulfamethoxazole as prophylaxis for opportunistic infections in human immunodeficiency virus (HIV)-infected post-natal Zambian women

niversity College London (UK)0 个研究点目标入组 600 人开始时间: 2009年4月22日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
600

研究概览

简要总结

2011 results in: https://www.ncbi.nlm.nih.gov/pubmed/21281407 (added 31/10/2019)

研究设计

研究类型
Interventional

入排标准

性别
Female

入选标准

  • 1. Women who have recently given birth
  • 2. Aged 16 years or more
  • 3. HIV-seropositive at stage 2 or 3 of the World Health Organization (WHO) staging system for HIV infection
  • 4. Evidence of residence at a permanent address in Lusaka
  • 5. Willing to attend at two-monthly intervals for follow-up
  • 6. Informed written or verbal consent

排除标准

  • 1. Current opportunistic infection or currently receiving co-trimoxazole
  • 2. History of sulphonamide allergy
  • 3. Breast feeding women with premature babies
  • 4. Advanced HIV-disease or serious non-HIV disease (i.e. unlikely to survive more than 2 weeks)

研究者

发起方
niversity College London (UK)

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