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Clinical Trials/ISRCTN76116512
ISRCTN76116512
Completed
未知

A double-blind, placebo controlled, randomized study comparing the effects of amitriptyline on dyspeptic symptoms in patients with functional dyspepsia

Academic Medical Center (AMC), Department of Gastroenterology (The Netherlands)0 sites38 target enrollmentMay 8, 2006
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ConditionsFunctional dyspepsiaDigestive SystemDyspepsia

Overview

Phase
未知
Intervention
Not specified
Conditions
Functional dyspepsia
Sponsor
Academic Medical Center (AMC), Department of Gastroenterology (The Netherlands)
Enrollment
38
Status
Completed
Last Updated
5 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2011 results in https://pubmed.ncbi.nlm.nih.gov/21767283/ (added 11/01/2021)

Registry
who.int
Start Date
May 8, 2006
End Date
May 1, 2009
Last Updated
5 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Academic Medical Center (AMC), Department of Gastroenterology (The Netherlands)

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 18\-65 years
  • •2\. Functional dyspepsia (Nepean Dyspepsia Index \[NDI] \>25\)
  • •3\. No effect on PPI, or 3 months constantly the same dose of PPI
  • •4\. No medications which influence the intestine
  • •5\. No depression (ZUNG \<50\)

Exclusion Criteria

  • •1\. Gastroduodenal surgery in history
  • •2\. Reflux\-like dyspepsia (Rome II criteria)
  • •3\. Use of antidepressants
  • •4\. Organic abnormalities
  • •5\. Severe cardiac, renal, pulmonary, hepatic or systemic diseases
  • •6\. Hyperthyroidism
  • •7\. Glaucoma and epilepsy

Outcomes

Primary Outcomes

Not specified

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