68Ga-PSFA PET Imaging in Patients With PSMA/FAP Positive Disease

First Affiliated Hospital of Chongqing Medical University1 site in 1 country30 target enrollmentMay 20, 2024

ConditionsPSMA FAP Positron-Emission Tomography

Interventions68Ga-PSFA

Drugs68Ga-PSFA

Overview

Phase: Early Phase 1
Intervention: 68Ga-PSFA
Conditions: PSMA
Sponsor: First Affiliated Hospital of Chongqing Medical University
Enrollment: 30
Locations: 1
Primary Endpoint: Diagnostic efficacy
Status: Recruiting
Last Updated: 11 months ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

As a new dual receptor (PSMA and FAP) targeting PET radiotracer, 68Ga-PSFA is promising as an excellent imaging agent applicable to PSMA/FAP positive diseases. In this research, we investigate the safety, biodistribution and potential usefulness of 68Ga-PSFA positron emission tomography (PET) for the diagnosis of lesions in PSMA/FAP positive diseases.

Registry

clinicaltrials.gov

Start Date

May 20, 2024

End Date

December 31, 2026

Last Updated

11 months ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

First Affiliated Hospital of Chongqing Medical University

Responsible Party

Principal Investigator

Xiaoyang Zhang

Principal Investigator

First Affiliated Hospital of Chongqing Medical University

Eligibility Criteria

Inclusion Criteria

•At least 18 years of age.
•Signed informed consent.
•Patients with suspected or newly diagnosed or previously malignant disease, with either PSMA or FAP positive expression (supporting evidence may include MRI, CT, and pathology report, etc).

Exclusion Criteria

•Patients with non-malignant disease.
•Patients with pregnancy.
•The inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.
•Known or expected hypersensitivity to 68Ga-PSFA or any of its components.
•Any serious medical condition or extenuating circumstance which the investigator feels may interfere with the procedures or evaluations of the study.