68Ga-PSMA PET/CT Imaging in Assessment of PCa: Feasibility of Delayed Acquisition on Total-body PET/CT Scanner?

RenJi Hospital1 site in 1 country66 target enrollmentDecember 1, 2020

ConditionsPET/CT Prostate Specific Membrane Antigen IMAGE

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: PET/CT
Sponsor: RenJi Hospital
Enrollment: 66
Locations: 1
Primary Endpoint: Only one-time point scan is possible for PSMA PET/CT
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Dual-time point 68Ga-PSMA PET/CT could increase the lesion detection in PCa patients, it remains difficult to perform in clinical practice. The possibility of one-time point 68Ga-PSMA PET/CT imaging could be achieved using a total-body PET/CT.

Registry

clinicaltrials.gov

Start Date

December 1, 2020

End Date

August 31, 2021

Last Updated

4 years ago

Study Type

Observational

Sex

Male

Investigators

Sponsor

RenJi Hospital

Responsible Party

Principal Investigator

Yumei Chen

deputy head of the department of nuclear medicine

RenJi Hospital

Eligibility Criteria

Inclusion Criteria

•primary staging of pathology-confirmed PCa or evidence of BCR with PSA value \> 0.2 ng/ml
•positive 68Ga-PSMA findings
•both standard and delayed scans were performed on the total-body PET/CT

Exclusion Criteria

•only one scan was performed
•negative PSMA results

Outcomes

Primary Outcomes

Only one-time point scan is possible for PSMA PET/CT

Time Frame: 8 months

By the use of total- body PET/CT scanner, the imaging quality between the 1 h p.i. and 3 h p.i. imaging acquisition are compared. And the different lesion detection rates at 3 h p.i. and 1 h p.i. are also discussed. The uptake value differences of all lesions are compared.