A Multidisciplinary Weight Loss Program at AUB-MC

Not Applicable

Active, not recruiting

• Conditions: Obesity; Weight Loss
• Interventions: Other: Standard Care; Other: Multidisciplinary weight loss program; Drug: Metformin Hcl 850Mg Tab

• Registration Number: NCT04194424
• Lead Sponsor: American University of Beirut Medical Center

Brief Summary

The current project aims at evaluating the feasibility and efficacy of a multi-disciplinary weight loss program, using an innovative and simple dietary intervention at the American University of Beirut Medical Center (AUB-MC). Such intervention is expected to enhance patients' compliance and adherence to lifestyle changes. In addition, the program includes supervised exercise sessions and behavioral therapy. Therefore, our project proposes an evidence based approach to close the obesity treatment gaps.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-07-18
• Study First Submitted QC: 2019-12-10
• Study First Posted: 2019-12-11
• Study Start: 2023-08-15
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-28
• Last Update Posted: 2025-01-29
• Primary Completion: 2026-09-15
• Study Completion: 2026-09-15

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Lebanese adult with obesity (≥18 years), obesity being defined as BMI ≥ 30 kg/m2
• Patients who can commit to frequent visit trials as per study protocol
• Patients not traveling outside Lebanon for at least the 6-month period of the trial
• Patients tolerating Metformin after a run-in period of 2 weeks

Exclusion Criteria

• Patients who have taken other weight reducing drug therapy in the previous 6 months
• Patients who have undergone bariatric therapy or endoscopic procedure, or planning to do so in the near future (at < 6 months)
• Patients with diabetes
• Patients working at AUB-MC, as we will not be able to assess the adherence to study visits nor the feasibility of such a program in the general population, presenting to AUB-MC only for clinical care
• A family member of a patient already enrolled in the study, as the participants will not be independent
• Pregnant obese patients
• Patients with pacemakers
• Patients known to have hypertension, cardiac, pulmonary, renal or liver disease, active cancer or psychiatric illnesses
• History of any surgery of less than 6 weeks duration
• Patients known to have disabling osteoarthritic or orthopedic problems
• Patients secondary uncontrolled endocrine disorders (thyroid disorders, polycystic ovary, Cushing disease), or drug induced obesity (such as anti-psychotic, steroids, hormonal therapy).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Multidisciplinary program	Metformin Hcl 850Mg Tab	Multidisciplinary weight loss program
Control	Standard Care	Standard care
Multidisciplinary program	Multidisciplinary weight loss program	Multidisciplinary weight loss program
Control	Metformin Hcl 850Mg Tab	Standard care

Primary Outcome Measures

Name	Time	Method
Mean percent weight loss per treatment arm	6 months after enrollment	\[(baseline weight-follow up weight at 6 months)/ baseline weight\] X 100

Trial Locations

Locations (1)

American University of Beirut - Medical Center; 🇱🇧 Beirut, Riad El Solh, Lebanon