Randomized controlled clinical trial to study effect of Kaishora Guggulu in vatarakta (Gout) with special reference to serum uric acid.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 主要终点
- to study add on effect of kaishora guggulu in the management of vatarakta (gout) with special reference to serum uric acid
研究概览
简要总结
vatarakta is disorder of VataDosha which is associated with DushyaRakta ,the chief complaint of patients is joint pain with onset from Hasta, Padangushtamulagata sandhi and then it migrates to other joints in a way similar to Akhuvisha.the disease which is most commonly seen in kudhavata i.e near the ankle or in smaller joints. the classical symptoms include Shvayathu, Bheda, Toda, Shoola, Sparshasahatva considering, the clinical presentation and textualreferences of the disease it can correlated with Gout explained in modern medicineGout is the most Common type of inflammatory arthritis and is associated with impaired quality of life. the formation and deposition of monosodium urate crystals takes place in and around joints as serum uric acid level rise and the physiological saturation threshold for uric acid is exceeded in the body fluids.Clinical manifestations of monosodium urate crystals deposition include acute of attacks of severe pain and inflammation affecting peripheraljoints, most commonly the first metatarso-phalangeal joint.modern lifestyle :1diet 2 loss exercise 3 night life:Due to night vigil pitta dosha gets increased and so raktadushti occurs.symptoms:Burning sensation, pain, joint pain, tenderness of joint, inflammation of joints, stiffness of joints.analgesic and other drugs may causes hyper acidity, which can be referred as pitta doshaprakop, which can increase a raktadosha.the present study kaishora guggulu is selected for vatarakta (gout) disease it includes guggulu, amalaki, guduchi, shunthi, haritaki, maricha, pippali, trivrit, danti, vidang, Bibhataki act on vata and Pitta,kaphajdosha helps in reducing Pain and Burning sensation, anti inflammatory, immunomodulation. which is easily available, Cost effective, palatable, reliable of patients,clinical method:- trial group:kaishora guggulu 500mg BD. treatment 30 day pt 30 control group:allopurinol pts-100mg-OD treatment 30 day pt 30
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •patient having sing and symptoms such as Sandhishoola, Sprashasahatva,Sandhishotha Stabdhata, Daha.
- •patient of either gender,irrespective of socioeconomic status.
排除标准
- •patient below 18 years and above 60 years old.
- •pregnant women and lactating mother.
- •knowncase of HIV.
- •knowncase Rheumatoid arthritis, Tubercular arthritis Syphilitic arthritis, Maleria, Neurological disorder.
- •knowncase of chikungunya knowncase of erythematous.
- •serum uric acid level more than 12mg/dl.
结局指标
主要结局
to study add on effect of kaishora guggulu in the management of vatarakta (gout) with special reference to serum uric acid
时间窗: 30 days
次要结局
- 1)To study vatarakta in detail according to ayurveda(2)To study gout in detail according to modern science)
研究者
Dr Snehal Uttamrao Ranvir
LRP Ayurvedic Medical College and Hospital, Post Graduate Institute and Research Center Islampur