A randomised controlled trial of bisphosphonate therapy in osteonecrosis of the hip.

Phase 2

Recruiting

• Conditions: osteonecrosis of the hip; collapse femoral head; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12609000104257
• Lead Sponsor: niversity of Sydney/ Northern Clinical School

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-02-13
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

symptoms of pain and disability in at least one hip joint and/or positive MRI findings stage I or II on the ARCO classification

Exclusion Criteria

Previous hip joint surgery on the affected hip and/or severe pain and disability at rest if treating clinician has recommended surgery and/or Radiographic or MRI findings suggestive for stage III and IV on the ARCO classification

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome of this project will be the number of patients progressing to stage III or IV on the Association Research Circulation Osseous (ARCO) scale on imaging (Magnetic Resonance Imaging (MRI)) at 12 months and with an X-ray at 36 months, including the number of patients requiring surgical intervention on the affected hip.[Measured at 12 months and 36 months]