Comparison of the effects of a combination of platelet-rich plasma and laser therapy versus a combination of platelet-rich plasma, laser therapy, and exercise therapy on pain intensity, disability, and quality of life in patients with knee osteoarthritis: a clinical trial study
Phase 3
Recruiting
- Conditions
- Knee osteoarthritis.Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting iM17. 9
- Registration Number
- IRCT20201001048893N4
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Mild to moderate osteoarthritis (OA) (2 or 3) as diagnosed by an orthopedic surgeon based on the Kellgren-Lawrence Grading Scale (KL)
No inflammatory and bleeding disorders
No rheumatoid arthritis
No endocrine and metabolic diseases
Imbalance and limping
No pregnancy
not perform procedures such as Arthrocentesis in the last six months
No joint surgery last year
Willingness to participate in the study
Exclusion Criteria
Failure to complete the course of treatment
Participant withdrawal from the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain intensity. Timepoint: Before treatment and 1, 3, and 6 months after treatment. Method of measurement: Numerical Rating Scale (NRS).
- Secondary Outcome Measures
Name Time Method Disability. Timepoint: Before treatment and 1, 3, and 6 months after treatment. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index (WOMAC).;Quality of life. Timepoint: Before treatment and 3, and 6 months after treatment. Method of measurement: 36-Item Short Form Survey (SF-36).