Extensive neurophysiological investigation in Guillain-Barré patients, focussing on motor unit abnormalities and weakness

Recruiting

• Conditions: GBS; Guillain-Barré syndrome; 10034606

• Registration Number: NL-OMON31256
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

*Age 18 years and older
*In acute phase of Guillain-Barré Syndrome
*Written informed consent

Exclusion Criteria

*severe other neurological or psychiatric disease
*Any psychological, familial, sociological and geographical condition potentially hampering compliance with the study protocol and follow-up schedule. Judgment is up to the investigator

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Change in motor units during the acute phase of the GBS.<br /><br>2)Abnormalities in neurophysiological investigation (axonal vs demyelinating)<br /><br>3)Existance of nerve terminal blocking</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>