Acupuncture-induced changes on brain excitability for stroke patients with motor dysfunctio
Completed
- Conditions
- Motor dysfunction after strokeNervous System Diseases
- Registration Number
- ISRCTN13358253
- Lead Sponsor
- Beijing Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. First-ever mono-hemispheric ischemic stroke
2. Within 14 days after stroke onset
3. Hand weakness with MRC level of 1 to 4
4. Aged between 18 and 80
Exclusion Criteria
1. Participation in other medical studies at present or during the previous 3 months
2. Pre-existing conditions of body dysfunction before stroke attack
3. Pregnancy
4. Cognitive or communication impairment or pre-existing conditions precluding informed consent or compliance with study assessments
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Excitability of primary motor cortex measured by recruitment curve of Motor Evoked Potential by transcranial magnetic stimulation at baseline and 3 months
- Secondary Outcome Measures
Name Time Method 1. Motor function of hand and arm are measured using the Action Research Arm Test and the upper-extremity portion of the Fugl-Meyer motor assessment at baseline and 3 months<br>2. General motor disability is measured using the modified Rankin scale at baseline and 3 months<br>3. Neurological deficit is measured using National Institutes of Health Stroke Scale assessment at baseline and 3 months<br>4. The muscle strength level is measured using the UK Medical Research Council standard at baseline and 3 months