ASSESSMENT OF LIVER STIFFNESS USING FIBROSCAN IN BETA THALASSEMIA CHILDREN : AN OBSERVATIONAL STUDY
Not Applicable
- Conditions
- Health Condition 1: D561- Beta thalassemia
- Registration Number
- CTRI/2021/04/033008
- Lead Sponsor
- Kasturba Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children diagnosed to have Beta Thalassemia major on regular blood transfusion between the age group 5-18 years admitted in the Department of Paediatrics Kasturba Medical College ,Manipal will be included
Exclusion Criteria
Children with Beta Thalassemia and diagnosed with any other liver pathology such as :
1.Hepatitis B,C,Wilsons Disease ,Autoimmune hepatitis
2.Obese children
3.Fatty liver will be excluded .
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of liver fibrosis using Fibroscan and finding a co-relation with serum ferritin levels,serum transaminases,iron chelation therapy and yearly transfusion requirement in thalassemia children .Timepoint: Assessment of liver fibrosis using Fibroscan and finding a co-relation with serum ferritin levels,serum transaminases,iron chelation therapy and yearly transfusion requirement in thalassemia children and comparing the findings with a repeat Fibroscan after one year.
- Secondary Outcome Measures
Name Time Method Assessment of liver fibrosis using Fibroscan and finding a co-relation with serum ferritin levels,serum transaminases,iron chelation therapy and yearly transfusion requirement in thalassemia children and comparing the findings with a repeat Fibroscan after one year.Timepoint: The findings will be compared with a repeat Fibroscan after one year.