on-invasive quantification of liver fibrosis with ultrasound: pilot

Completed

• Conditions: liver fibrosis; liver scarring; 10019654

• Registration Number: NL-OMON37760
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Group 1: 25 healthy volunteers, age 25-70 years, BMI 20-40
Group 2: 25 patients with histologically confirmed cirrhosis, age > 18 years

Exclusion Criteria

Group 1
History of liver disease
Excessive alcohol use (> 25 consumptions per week for men, > 10 consumptions per week for women)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study outcomes are:<br /><br>• Reference intervals<br /><br>• Intra- and interobserver variability<br /><br>To this end, the following variables will be measured / calculated: strain (for<br /><br>elastography) and inhomogeneity (for ASQ), their variances, the corresponding<br /><br>effect size and coefficients of agreement.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>nvt</p><br>