A study of non invasive evaluation of liver fibrosis in patients with Hepatitis B Virus(HBV) monoinfection using Fibroscan (Transient Elastography)
- Conditions
- Hepatitis B Virus (HBV)Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon
- Registration Number
- ACTRN12609000381280
- Lead Sponsor
- Alfred Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 250
Chronic hepatitis B infection.
Subjects having a liver biopsy as part of routine standard of clinical care.
Body mass index < 36.
Co-infection with Human Immunodeficiency Virus(HIV), HepatitisC Virus(HCV), or Hepatitis D Virus (HDV).
Evidence of other causes of chronic liver disease.
Decompensated liver disease including ascites.
Evidence of alcohol abuse (> 20 gm/day) during the last 6 months.
Anticipated or current use or need for significant concomitant medical treatment including but not limited to systemic immunosuppressive drugs, cytotoxics, or chemotherapeutic agents.
History of recent acute hepatitis.
Clinical or radiological suspicion of Hepatocellular Carcinoma(HCC).
Presence of bleeding disorder.
Presence of cardiac pacemaker.
Contraindication to liver biopsy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method