NCT06170580已完成不适用
Improved Image Quality for Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound FLOW Imaging
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- 2D velocity vector fields obtained by plane wave and cascaded wave imaging of the carotid artery
研究概览
简要总结
Objective: To evaluate the technical performance of a novel cascaded wave imaging technique compared to plane wave imaging for blood flow imaging in patients with and without carotid artery stenosis.
Study design: Observational, feasibility study in a total of 10 patients with and 10 patients without a hemodynamic significant carotid artery plaque.
Intervention (observational): all participants will undergo a carotid ultrasound measurement including conventional duplex ultrasound and ultrasound based flow imaging using plane waves and cascaded waves.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Capacitated adult male or female (≥18 years old);
- •Informed consent form understood and signed;
- •Recent conventional duplex measurement of the carotid artery confirming either the absence or presence of a plaque
排除标准
- •Hampered carotid blood flow imaging during conventional duplex/doppler measurements due to near to total carotid occlusion at the side of interest or a calcified plaque;
- •History of radiation at the head-neck area;
- •Participating in another clinical study, interfering on outcomes.
结局指标
主要结局
2D velocity vector fields obtained by plane wave and cascaded wave imaging of the carotid artery
时间窗: After study completion, average of one year
次要结局
- Cross-correlation maps of plane wave and cascaded wave imaging will be obtained and compared for different vessel depths(After study completion, average of one year)
- Velocity vector fields obtained from plane wave and cascaded wave imaging will be obtained and compared(After study completion, average of one year)
- Blood-flow related parameters, including vector complexity and vorticity, will be calculated from 2D velocity fields.(After study completion, average of one year)
- Spatiotemporal blood flow profiles obtained with plane wave, cascaded wave and conventional duplex ultrasound will be compared to assess the correlation between these techniques(After study completion, average of one year)
- Signal-to-noise ratio obtained from plane wave and cascaded wave imaging will be obtained and compared for different vessel depths(After study completion, average of one year)
研究者
研究点 (1)
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