Comparison of serum sodium levels following intravenous administration of isotonic and hypotonic solutions in young children: a randomized controlled trial
Phase 3
Completed
- Conditions
- changing of serum sodium after 24 hr intravenous fluid administrationhypotonic solutions, isotonic solutions, hyponatremia, metabolic acidosis, children
- Registration Number
- TCTR20201212004
- Lead Sponsor
- avamindradhiraj University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
1. Patients from 3 months to 5 years of age who admitted and require maintenance intravenous fluid solution
2. Initial serum sodium 130-140 mEq/
Exclusion Criteria
1. Patients with neurological disorders
2. Patients with congenital heart or acquired heart disease
3. Patients with hepatic disease
4. Patients with cancer
5. Patients with renal dysfunction
6. Patients with adrenal insufficiency
7. Patients with diabetes insidious
8. Patients with voluminous watery diarrhea
9. Patients with shock
10. Patients who had history of electrolyte imbalance
11. Patients who receive medication affect serum sodium e.g. diuretic
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study change in serum Na following the administration of hypotonic versus isotonic IVFS at 24 hour 24 hours after administration intravenous fluid serum sodium
- Secondary Outcome Measures
Name Time Method To study Incidence of hyponatremia and hypernatremia 24 hours after administration intravenous fluid serum sodium,To study incidence of metabolic acidosis 24 hours after administration intravenous fluid serum HCO3, pH,To study change in serum Na following the administration of hypotonic versus isotonic IVFS at 48 hou 48 hours after administration intravenous fluid serum sodium