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Clinical Trials/NCT05782504
NCT05782504
Recruiting
Not Applicable

Patient-centered Teleprehabilitation for Women With Breast Cancer: a Feasibility Study

Universitair Ziekenhuis Brussel2 sites in 1 country50 target enrollmentJanuary 30, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Breast Cancer
Sponsor
Universitair Ziekenhuis Brussel
Enrollment
50
Locations
2
Primary Endpoint
Incidence of treatment-emergent adverse events (safety and tolerability)
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

Surgery, the cornerstone of most cancer treatments, is associated with considerable postoperative complications. Adjusting patients' health behavior before surgery may have beneficial effects on postoperative outcomes.

Women (n=50) who will undergo breast surgery because of stage I-III breast cancer are eligible. All participants will receive multimodal patient-centered teleprehabilitation comprising of motivational interviewing, education, exercise therapy, and stress management.

Detailed Description

Feasibility, participation rate, patient satisfaction, intervention safety, and treatment adherence will be monitored as primary outcomes. Fatigue, pain, quality of life (QoL), physical activity levels, perceived injustice, self-efficacy, and healthcare use are secondary outcomes and will be assessed by self-reported questionnaires at baseline, 0-, 2-, and 6 months post-intervention. Proof of concept for using telecommunication and exercise therapy in prehabilitation prior to breast cancer surgery is available. We expect the proposed intervention to be feasible and effective at reducing fatigue, pain, perceived injustice, and healthcare use, and at improving treatment adherence, QoL, physical activity levels, and self-efficacy. Effective prehabilitation interventions can reduce the long-term symptoms that arise/persist beyond treatment completion, improving patients' QoL. By using telecommunication technologies, socio-economic barriers can be reduced, making care accessible to all.

Registry
clinicaltrials.gov
Start Date
January 30, 2023
End Date
August 31, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Aged 18 years or older
  • Scheduled for primary breast surgery because of stage I-III breast cancer
  • Able to speak and read Dutch fluently

Exclusion Criteria

  • Stage IV breast cancer
  • A medical contra-indication for physical activity
  • Not being able to access a computer or mobile device at home

Outcomes

Primary Outcomes

Incidence of treatment-emergent adverse events (safety and tolerability)

Time Frame: within one week after completion of the intervention

To examine the safety of the intervention, participants will be asked whether they experienced any side effects or unexpected events associated with the intervention after each treatment session.

Feasibility of teleprehabilitation in the clinical setting by means of focus group discussions with stakeholders

Time Frame: through study completion, an average of 1 year

The feasibility of the patient-centered teleprehabilitation intervention in the clinical setting will be investigated using focus group discussions with all the involved care providers.

Patient satisfaction with the teleprehabilitation intervention (feeling of contentment with the intervention)

Time Frame: within one week after completion of the intervention

This will be assessed using a questionnaire ending with an open question ('To what extent is this what you needed? Please explain your answer') and the possibility to suggest alternative treatment content. Patient satisfaction with teleprehabilitation will also be assessed using in-depth interviews with all study participants.

Adherence to treatment (compliance rate)

Time Frame: within one week after completion of the intervention

The compliance rate for the teleprehabilitation sessions will be calculated as the ratio of the number of followed treatment sessions versus the number of planned treatment sessions. Next to the supervised sessions, patients will also have sessions without direct supervision that they will have to carry out themselves at home (i.e., exercise sessions, relaxation exercises, and reading the information leaflet). Patients will be asked to record these unsupervised therapy sessions in a personal logbook. The compliance with these home exercise sessions is calculated as the ratio between the number of sessions performed and the number of sessions prescribed.

Participation rate

Time Frame: one day before the start of the intervention

This will be calculated as the ratio of the number of patients participating in the study to the number of patients eligible for study participation. Along with that, the participation rate for each of the secondary outcome measures (see further) at each of the time points (baseline and follow-up) will be recorded.

Secondary Outcomes

  • Healthcare and medication use during the study period(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)
  • Pain (uncomfortable sensations in the body)(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)
  • Subjective level of physical activity(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)
  • The feeling of perceived injustice(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)
  • Fatigue (feeling of tiredness or lack of energy)(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)
  • Quality of Life (the degree to which an individual is healthy, comfortable, and able to participate in or enjoy life events)(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)
  • Self-efficacy (self-beliefs to cope with a variety of difficult demands in life)(one day before the start of the intervention, one week after completion of the intervention, 30 days after breast surgery, 6 months after breast surgery)

Study Sites (2)

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