Light and Sleep Fragmentation

Phase 4

Not yet recruiting

• Conditions: Mild Cognitive Impairment; Mood Disorders; Sleep

• Registration Number: NCT06009289
• Lead Sponsor: Stanford University

Brief Summary

This trial will examine scheduled exposure to bright light in the morning and afternoon as a countermeasure to sleep fragmentation in older individuals with mild cognitive impairment.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-08
• Study First Submitted: 2023-08-18
• Study First Submitted QC: 2023-08-18
• Last Update Submitted: 2023-08-23
• Study First Posted: 2023-08-24
• Last Update Posted: 2023-08-25
• Study Start: 2026-06-01
• Primary Completion: 2028-05-30
• Study Completion: 2028-05-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Mild Cognitive Impairment
• Age >65

Exclusion Criteria

• Severe depression
• Unstable psychiatric or medical disease
• Acute infection

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Primary Outcome Measures

Name	Time	Method
Sleep fragmentation	4 weeks	24 hour sleep wake patterns will be quantitated with a non-parametric measure, intradaily variation

Secondary Outcome Measures

Name	Time	Method
Cognition	6 months	Performance on the WAIS-4
Mood	6 months	Geriatric Depression Scale, range: 0-15 with higher scores being associated with greater depressive symptomatology

Trial Locations

Locations (1)

Stanford University; 🇺🇸 Redwood City, California, United States